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Brand name:


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Alphagan is also used to treat ocular hypertension, or high pressure occurring inside the eye
Mirvaso And Alphagan P
Prescription needed
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Alcohol can negatively affect the joint intake with the drug
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For informational purposes only. Consult your local medical authority for advice.

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What should my health care professional know before I take Alphagan?

You should not use brimonidine ophthalmic if you are allergic to it. To make sure brimonidine ophthalmic is safe for you, tell your doctor if you have:

  • congestive heart failure, coronary artery disease, history of stroke or blood clot;
  • low blood pressure, circulation problems (such as Raynaud's syndrome);
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  • any allergies; or
  • a history of glaucoma or increased pressure inside your eye.

Brimonidine ophthalmic should not be given to a child younger than 2 years old. FDA pregnancy category B. Brimonidine ophthalmic is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether brimonidine ophthalmic passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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Adrian is a Co-Founder of Accreto Solutions. He works with advisory firms to find high level strategic solutions for their growth plans, including acquisitions and senior team moves…

His client base spans management, strategic and specialist consultancies, financial advisors and operational turnaround specialists.

Prior to forming Accreto Solutions, Adrian was a founding partner of Riverhouse Solutions. He has spent more than 20 years working with clients who have been pioneers in both developed and emerging markets. This experience has ingrained in him a creative and proactive approach to helping clients grow their businesses and explains his tenacious style.

He still maintains a professional interest in emerging markets. Building on an extensive professional network in many emerging and frontier markets, Adrian has advised banks, funds and advisory firms on how best to position themselves within these often complex and developing markets.
 He holds a BA in Business Studies from Brunel University and speaks fluent French and Spanish.



As a Co-Founder of Accreto Solutions, Dominic works closely with advisory firms looking to strengthen existing businesses as well as with new entrants to the market…

These firms operate across management and strategic consultancy, financial advisory and asset management. Increasingly, this includes issues and opportunities around ESG.

After 20 years of advising clients on senior hires and key team builds, Dominic takes a strategic, business solution-driven approach to search. This approach is essential in partnering with Accreto Solutions’ clients on business acquisitions and on building effective platforms from scratch.

Dominic’s prior search career was spent primarily focusing on investment banks’ pan-European markets platforms across all asset classes, where he was involved in multiple team build-outs on behalf of global banks. He holds a BSc from the London School of Economics in Political Science.




To assist a major financial institution in adding additional advisory services to its European-centric M&A business. Areas considered were M&A, debt restructuring, debt advisory and equity advisory. Whilst an acquisition was preferred, we were also asked to look at potential team hires without onerous non-compete clauses in their contracts.


Extensive research and due diligence were required to advise our client on which advisory services would provide the best ROE. Since some advisory services are highly cyclical, we also wanted to ensure our client wasn’t overpaying for an impressive ROE that was performing at its peak or underpaying for modest returns that could shortly take off. Furthermore, it was necessary to ensure a good cultural fit and the long-term benefit from the acquisition for both parties. As this project took place over the 2016 European referendum, we also had to analyse the positive and negative impacts this might have.


We conducted a thorough mapping of the potential acquisition opportunities where we felt there was sufficient upside to warrant an acquisition.  We also looked at teams whose contracts were domiciled in jurisdictions where non-compete clauses were not relevant. We shortlisted five institutions, covering three different advisory services. These were extensively referenced in a confidential manner leading the client to reduce this list to two.




A US client wanted to expand their strategic consultancy offering to include dedicated coverage of the UK and Continental Europe.


Strategic consultancies come in many forms.  Although the brief was to identify businesses of an appropriate size that had the experience and knowledge-base to operate with Global 1000 companies, our challenge was finding consultancies whose culture could match the entrepreneurial and creative demands of our client.  We also needed to ensure that the target consultancies’ expertise wasn’t restricted to one or two sectors and that the advice they offered related to major strategic changes or challenges.  They would also have to be able to operate within a very team-orientated culture where service divisions are actively encouraged to leverage their combined knowledge and experience.

As our US-based client had limited availability for meetings with target companies, we had to ensure that every target on the shortlist both fitted the brief and was motivated to engage.


Through extensive conversations with target companies and cross-referring our information, we identified a very select shortlist.  This enabled the client to focus quickly on the most suitable targets, leading to successful completion of the acquisition within 6 months of the initial engagement.